Self reported adverse effects of mono and polytherapy for epilepsy
نویسندگان
چکیده
منابع مشابه
Self reported adverse effects of mono and polytherapy for epilepsy
PURPOSE Adverse effects of anti epileptic drugs (AEDs) can significantly affect the life of people with epilepsy. We used a register to determine if polytherapy with AED has more adverse effects than monotherapy. METHODS We established a register for people with epilepsy (www.UKAED.info). Participants were requested to complete the Liverpool Adverse Event Profile (LAEP) to quantify adverse ef...
متن کاملReappraisal of polytherapy in epilepsy: a critical review of drug load and adverse effects.
PURPOSE We reviewed the literature to determine whether an analysis of published data could clarify the relationship between antiepileptic drug (AED) polytherapy and adverse affects (AE). We highlight the problems encountered. METHODS We made a Medline-search for articles published between 1974 and 1994 reporting the number of AE and doses or serum levels of every AED, per patient or treatmen...
متن کاملMonotherapy or polytherapy for epilepsy?
Monotherapy has been promoted as the ideal in epilepsy treatment because of reduced side effects, absence of drug interactions, better compliance, lower cost and, in many cases, improved seizure control compared to polytherapy. The question of monotherapy vs. polytherapy has assumed increasing importance with the availability of multiple new antiepileptic drugs (AEDs), initially tested as add-o...
متن کاملAdverse effects & drug load of antiepileptic drugs in patients with epilepsy: Monotherapy versus polytherapy
BACKGROUND & OBJECTIVES Although the need for a combination of antiepileptic drugs (AEDs) in the treatment of epilepsy is well justified, but an associated increase in adverse effects (AEs) lends a restriction to polytherapy. The aim of this study was to evaluate AEs and drug load (prescribed daily dose/defined daily doses) of AEDs in patients with epilepsy (PWE). METHODS Consecutive PWEs att...
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although there are studies on pragmatic assessment, to date, literature has been almost silent about native and non-native english raters’ criteria for the assessment of efl learners’ pragmatic performance. focusing on this topic, this study pursued four purposes. the first one was to find criteria for rating the speech acts of apology and refusal in l2 by native and non-native english teachers...
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ژورنال
عنوان ژورنال: Seizure
سال: 2012
ISSN: 1059-1311
DOI: 10.1016/j.seizure.2012.06.013